Thanks to John for presenting the case of a middle-aged woman with metastatic renal cell carcinoma who presented with subacute diffuse weakness and constipation, found to have symptomatic hypercalcemia, treated with IV fluids and zoledronic acid. Clinical Pearls A third of patients with malignancy develop hypercalcemia in their disease course.  Hypercalcemia of malignancy is associated … Continue reading Hypercalcemia of malignancy