- Autoimmune hepatitis: Type 1 (associated with Anti-smooth muscle antibody which is very specific) and Type 2 (Anti-LKM), more common in women 4:1, can also be associated with elevated IgG
- Diagnose autoimmune hepatitis with liver biopsy showing interface hepatitis
- Treatment for autoimmune hepatitis includes prednisone plus azathioprine or prednisone alone, liver transplantation when no contraindications
- Generally lupus is not usually a cause of liver disease but can be associated with autoimmune hepatitis
- SLE: Anti-DS DNA is used to follow disease progression
SCVMC IM Chief Resident Blog 