Morning Report 8/13/15: Serotonin Syndrome

Great Discussion!

  NMS Serotonin Syndrome
Etiology Too Little Dopamine Too much serotonin
Onset Days to Weeks Usually < 24 hours (more acute than NMS)
Neuromuscular Findings Bradyreflexia, severe muscular rigidity Hyperreactivity (tremor, myoclonus, reflexes, ocular clonus)
Pupils Normal Dilated
Treatment Supportive care, consider bromocriptine Benzodiazepines, cyproheptadine in certain cases
Resolution Days to weeks < 24 hours

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