Sweet Syndrome

We discussed a case of a young woman w/ refractory AML, who was admitted for relapse of AML and developed new acute edematous (“juicy”), violaceous plaques, found to have Sweet syndrome.

Types

  • Idiopathic (classic)
  • Malignancy-associated
  • Drug-associated

Clinical manifestations

  • Abrupt, painful, edematous (“juicy”), erythematous / violaceous
  • Papules / plaques / nodules

Diagnosis

  • Clinical assessment and diagnostic criteria (there are criteria for idiopathic and for drug-associated)
  • Biopsy

Treatment

  • Systemic glucocorticoids (1st line)

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