Sticky Klebsiella (Hypermucoid variant)
Diagnosis of Hypermucoid variant Klebsiella (Hypermucoviscosity phenotype)
String test done in lab after identifying Klebsiella pneumoniae, + test is >5 mm viscous string from the colony on an agar plate
(c) Andres Rivero et al. J. Clin. Microbiol. 2010;48:639-641
Risk factors for KLA (Klebsiella Liver Abscess)
DMII (poor neutrophil control impairs neutrophil phagocytosis of capsular subtypes)
Asian descent (especially Taiwan)
Prior antibiotic use
Clinical manifestations
Fever (93 %)
RUQ tenderness (71 %)
N/V/diarrhea
Leukocytosis
Complications (in addition to liver abscess)
Endolphalmitis (ask about ocular symptoms daily!)
Meningitis, Brain Abscess
Treatment
Drainage of liver abscess
Cephalosporins (commonly CTX), can add Flagyl if anaerobic coverage needed, plan for 4-6 weeks antibiotic course depending on resolution of abscess